Preheat your oven to 350°F (175°C).
In a mixing bowl, combine the melted butter, garlic powder, onion powder, dried parsley, salt, black pepper, and cayenne pepper. Mix well until all ingredients are combined.
Place the Ritz crackers in a large mixing bowl. Pour the butter mixture over the crackers and gently toss until all crackers are evenly coated.
Spread the coated crackers in a single layer on a baking sheet lined with parchment paper.
Sprinkle the grated Parmesan cheese evenly over the crackers.
Bake in the preheated oven for 10-12 minutes, or until the crackers are golden and crispy.
Remove from the oven and let cool for a few minutes before serving.