In a large mixing bowl, combine ground chicken, chipotle peppers, adobo sauce, smoked paprika, cumin, garlic powder, onion powder, salt, black pepper, lime juice, breadcrumbs, and egg. Mix until well blended.

Divide the mixture into four equal portions and shape each into a patty about 1 inch thick, making a slight indentation in the center.

Heat a grill or skillet over medium heat. Cook patties for 5-6 minutes on each side until golden brown and internal temperature reaches 165°F.

If using cheese, place a slice on each patty during the last minute of cooking, covering to help it melt.

While patties cook, prepare chipotle mayo by whisking together mayonnaise, chopped chipotle pepper, lime juice, garlic powder, and salt.

To assemble, toast burger buns, spread chipotle mayo on the bottom half, and layer with lettuce, chicken patty, sliced tomatoes, onions, and jalapeños. Top with the other half of the bun.

Serve immediately with sides like fries or salad.