Creamy Chicken and Spinach Casserole: A Rich and Comforting Meal

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There’s something undeniably comforting about a warm, cheesy, and creamy casserole fresh out of the oven. This Creamy Chicken and Spinach Casserole is the perfect dish when you’re craving something hearty, flavorful, and satisfying without spending hours in the kitchen.

With tender chicken, creamy spinach, and layers of melted cheese, this dish is a crowd-pleaser that works for busy weeknights, potlucks, or even special occasions. Best of all, it’s easy to make, low-carb, and packed with protein!

Let’s dive into the details so you can make this delicious creamy spinach chicken casserole at home!

Why You’ll Love This Recipe

✔️ Rich and Creamy: A luscious blend of cream cheese, mozzarella, and Parmesan.
✔️ High-Protein & Low-Carb: A great option for those on a keto-friendly diet.
✔️ One-Pan Wonder: Everything bakes together in a single dish—minimal cleanup!
✔️ Perfect for Meal Prep: Stays moist and delicious when reheated.
✔️ Customizable: Adjust the cheese, seasoning, or add extra vegetables!

Ingredients for Creamy Chicken and Spinach Casserole

Here’s everything you need for this flavor-packed, cheesy casserole:

IngredientQuantity
Boneless, skinless chicken breasts2 large
Olive oil (divided)2 tbsp
Garlic (minced)3 cloves
Italian seasoning1 tbsp
Salt½ tsp
Black pepper½ tsp
Fresh spinach2 cups
Cream cheese (softened)8 oz
Shredded mozzarella cheese (divided)1 cup
Parmesan cheese (optional)½ cup

How to Make Creamy Chicken and Spinach Casserole

1. Preheat the Oven

  • Set your oven to 400°F (200°C).
  • Lightly grease a 9×13 inch baking dish with butter or cooking spray.

2. Prepare the Chicken

  • Cut the chicken breasts in half horizontally to create four thinner pieces.
  • Pound the thicker ends with a rolling pin so they are evenly sized.

3. Marinate the Chicken

  • In a large bowl, whisk 1 tablespoon of olive oil, minced garlic, Italian seasoning, salt, and black pepper.
  • Add the chicken pieces, toss to coat, then cover and chill for 15-30 minutes.

4. Sauté the Spinach

  • Heat the remaining 1 tablespoon of olive oil in a large skillet over medium heat.
  • Add the spinach and cook, stirring frequently, until wilted (about 2-3 minutes).
  • Set aside.

5. Prepare the Cream Cheese Mixture

  • In a medium bowl, beat the softened cream cheese until smooth.
  • Stir in the wilted spinach, ½ cup shredded mozzarella, and Parmesan (if using).
  • Mix until smooth and well combined.

6. Assemble the Casserole

  • Remove the chicken from the marinade and let the excess drip off.
  • If desired, sear the chicken in the skillet for 1-2 minutes per side for extra flavor.
  • Arrange the chicken pieces in a single layer in the baking dish.
  • Spread the cream cheese and spinach mixture evenly over the chicken.
  • Sprinkle the remaining mozzarella cheese on top.

7. Bake the Casserole

  • Bake for 20-30 minutes or until the chicken is fully cooked (165°F or 75°C) and the cheese is melted and lightly browned.

8. Rest & Serve

  • Let the casserole rest for 5 minutes before serving.
  • Garnish with fresh parsley or extra Parmesan and enjoy!

Best Side Dishes for Creamy Chicken and Spinach Casserole

This dish pairs wonderfully with:

Caesar Salad: A crisp and fresh contrast to the creamy casserole.
Steamed or Roasted Vegetables: Try broccoli, carrots, or zucchini.
Garlic Butter Rice: Soaks up the rich, cheesy sauce beautifully.
Mashed Potatoes: A perfect pairing for ultimate comfort food.
Warm Dinner Rolls: Ideal for scooping up extra sauce.

Tips for the Best Creamy Chicken and Spinach Casserole

Use Fresh Spinach: Frozen spinach works, but fresh spinach gives the best flavor and texture.
Don’t Skip the Marinating Step: It helps the chicken stay juicy and absorb flavor.
Let the Cheese Brown: Broil for 2-3 minutes at the end for a crispy golden top.
Make it Extra Cheesy: Add an extra layer of shredded cheese for extra richness.
Adjust the Creaminess: If you want a thinner sauce, stir in a splash of heavy cream or chicken broth.

Variations & Substitutions

🔹 Make It Spicy: Add red pepper flakes or cayenne pepper for a kick.
🔹 Use Chicken Thighs: Swap breasts for boneless, skinless thighs for extra juiciness.
🔹 Try a Different Cheese: Use Gruyère, Swiss, or Monterey Jack instead of mozzarella.
🔹 Add More Veggies: Stir in mushrooms, sun-dried tomatoes, or bell peppers.
🔹 Make It Low-Carb: Serve over cauliflower rice or zucchini noodles instead of pasta.

How to Store & Reheat Leftovers

Refrigeration

  • Store in an airtight container in the fridge for up to 3 days.

Freezing

  • Freeze in an airtight container for up to 2 months.
  • Thaw overnight in the fridge before reheating.

Reheating

  • Oven: Warm at 350°F (175°C) for 15 minutes until heated through.
  • Microwave: Heat in 30-second intervals, stirring between each round.

Frequently Asked Questions

1. Can I use frozen spinach?

Yes! Just thaw and drain it well to remove excess moisture.

2. How do I know when my chicken is fully cooked?

Use a meat thermometer—it should read 165°F (75°C) in the thickest part.

3. Can I make this dish ahead of time?

Absolutely! Assemble the casserole, cover, and refrigerate for up to 24 hours before baking.

4. What’s the best way to make this casserole extra creamy?

  • Use full-fat cream cheese.
  • Add a splash of heavy cream to the mixture.

5. Can I make this in a slow cooker?

Yes! Cook on low for 4-5 hours, then add the cheese in the last 30 minutes.

6. What’s the best cheese for this recipe?

Mozzarella is melty and mild, but Gruyère, Swiss, or even feta add a unique twist.

Final Thoughts

If you’re looking for a rich, creamy, and delicious casserole, Creamy Chicken and Spinach Casserole is a must-try. With tender chicken, a cheesy spinach filling, and a perfectly golden top, this dish is comfort food at its best.

So grab your ingredients, follow these easy steps, and enjoy a restaurant-quality meal at home! 🍽️

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Creamy Chicken and Spinach Casserole: A Rich and Comforting Meal


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  • Author: Emma
  • Total Time: 35 minutes
  • Yield: 4 servings

Description

Creamy Chicken and Spinach Casserole is the ultimate comfort food! Tender chicken, creamy spinach, and melted cheese come together in a rich, flavorful dish that’s perfect for busy weeknights or special occasions. This easy, one-pan meal is packed with protein and low in carbs, making it a deliciously satisfying option for the whole family.


Ingredients

  • 2 large boneless, skinless chicken breasts
  • 2 tablespoons olive oil (divided)
  • 3 cloves garlic (minced)
  • 1 tablespoon Italian seasoning
  • ½ teaspoon salt
  • ½ teaspoon black pepper
  • 2 cups fresh spinach
  • 8 oz cream cheese (softened)
  • 1 cup shredded mozzarella cheese (divided)
  • ½ cup Parmesan cheese (optional)

Instructions

  • Preheat the Oven
    • Set your oven to 400°F (200°C).
    • Lightly grease a 9×13-inch baking dish with butter or cooking spray.
  • Prepare the Chicken
    • Slice chicken breasts in half horizontally to create four thinner pieces.
    • Pound the thicker ends with a rolling pin to ensure even thickness.
  • Marinate the Chicken
    • In a large bowl, mix 1 tablespoon olive oil, minced garlic, Italian seasoning, salt, and black pepper.
    • Coat the chicken pieces in the marinade, cover, and refrigerate for 15-30 minutes.
  • Sauté the Spinach
    • Heat the remaining 1 tablespoon olive oil in a skillet over medium heat.
    • Add spinach and cook, stirring, until wilted (about 2-3 minutes).
    • Set aside.
  • Prepare the Cream Cheese Mixture
    • In a bowl, beat the softened cream cheese until smooth.
    • Stir in the wilted spinach, ½ cup shredded mozzarella, and Parmesan (if using).
    • Mix until well combined.
  • Assemble the Casserole
    • Arrange the chicken pieces in a single layer in the baking dish.
    • Spread the cream cheese and spinach mixture evenly over the chicken.
    • Sprinkle the remaining mozzarella cheese on top.
  • Bake the Casserole
    • Bake for 20-30 minutes or until the chicken reaches an internal temperature of 165°F (75°C) and the cheese is golden and bubbly.
  • Rest & Serve
    • Let the casserole rest for 5 minutes before serving.
    • Garnish with fresh parsley or extra Parmesan, if desired.

Notes

  • Use fresh spinach for the best texture and flavor. If using frozen, drain it well.
  • Let the cheese brown by broiling for 2-3 minutes at the end.
  • Make it extra creamy by adding a splash of heavy cream or chicken broth.
  • Sear the chicken first for a richer flavor before baking.
  • Prep Time: 10 minutes
  • Cook Time: 25 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American

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